Objectives



  1. Discuss what is meant by the term “transplant”.
  2. Discuss the molecular basis for graft acceptance/rejection (i.e., transplantation antigens).
  3. Discuss why some grafts are rejected and others are not.
  4. State why immunosuppressive drugs are needed for “foreign” grafts.
  5. Describe how organ donors are obtained.



1) Discuss what is meant by the term "transplant":

There are four main types of transplant:

1) Autograft: A transplant of one's own tissue to oneself.
2) Allograft: A transplant from a genetically non- identical member of the same species.
3) Isograft: A transplant from a genetically identical member of the same species.
3) Xenograft: A transplant from one species to another.

Success for transplantation depends on the degree of compatibility between the donor and recipient and often immunosuppressant drugs are given to patients following a transplant.